In the ever-advancing world of aesthetic medicine, a new frontier in skin rejuvenation is emerging polynucleotides. Once reserved for advanced regenerative medicine, these bio-revitalising injectables are now making waves in the beauty space as the next generation of skin boosters. At Macsoflondon Medical Aesthetics & Wellness Clinic, we stay ahead of the curve, offering our clients only the most effective, scientifically-backed treatments to help them age gracefully, naturally, and beautifully.

What Are Polynucleotides?

Polynucleotides (PNs) are chains of DNA molecules derived from salmon or trout DNA, highly purified for human use. They work by promoting deep skin regeneration at a cellular level, stimulating fibroblasts, encouraging collagen and elastin production, and significantly improving tissue quality. Unlike hyaluronic acid-based skin boosters, polynucleotides do not simply hydrate they regenerate.

The Science Behind Polynucleotide Therapy

When injected into the skin, polynucleotides:

- Boost fibroblast activity, increasing production of collagen and elastin

- Improve skin elasticity and density

- Enhance skin hydration and reduce inflammation

- Speed up tissue healing and repair

This regenerative action makes polynucleotides particularly effective for:

- Crepey, lax, or sun-damaged skin

- Fine lines and wrinkles

- Acne scarring

- Under-eye rejuvenation

- Skin prone to inflammation or rosacea

Polynucleotides vs Traditional Skin Boosters

While hyaluronic acid (HA) remains a gold standard for skin hydration, polynucleotides go several steps further by working on skin quality and structure, not just volume.

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At Macsoflondon, we often recommend polynucleotides to clients seeking a more natural, regenerative approach to skin rejuvenation, especially in delicate areas such as under the eyes, neck, and décolletage.

Are Polynucleotides Safe?

Absolutely. Polynucleotides have been used in medicine for decades, particularly in ophthalmology and orthopaedics. In aesthetics, they’re considered exceptionally safe, with minimal risk of allergic reaction due to their high purification. Side effects are typically mild and may include temporary redness, swelling, or bruising at the injection site.

Who Is a Good Candidate?

Polynucleotides are ideal for clients who:

- Are experiencing early signs of ageing

- Want to improve skin tone and texture

- Have sensitive or acne-prone skin

- Prefer a subtle, natural look

Clients in their late 20s to 60s have all benefited from polynucleotide therapy, making it a versatile treatment suitable for various skin types and concerns.

Ready to Try the Next Evolution in Skin Boosters?

Discover the skin-regenerating power of polynucleotides at our award-winning London clinic.

📅 Book your personalised consultation today and take the first step towards luminous, healthier skin.